Dr Richard Mort
Senior Lecturer in Cell and Developmental BiologyProfile
My resreach interests are in applying imaging based methods to understand development, tissue homoeostasis and disease with a particular interest in pigmentation and melanoma.
Lab web pages: http://wp.lancs.ac.uk/mortlab/
Research Interests
Melanocytes and melanoma: Melanocytes are the cells in our skin and hair that produce pigment. Melanoma, a cancer of melanocytes, is one of the deadliest forms of skin cancer. Its incidence has increased 7-fold in men and 4-fold in women in the last 40-years. The risk of developing melanoma is exacerbated by exposure to UV radiation in sunlight/sunbed lamps. My research is concerned with the early development of the melanocyte lineage and the lineage relationships and behaviour of the adult melanocyte populations and their roles in melanoma.
Biosensors of tissue homoeostasis: Biosensors that mark cell cycle stage allow real time visualisation of cell cycle dynamics in cell culture, during embryonic development and in tissue homoeostasis. Fucci was developed by Prof. Atsushi Miyawaki and Dr. Asako Sakaue-Sawano (RIKEN, Japan) and incorporates genetically encoded probes that highlight G1 and S/G2/M phases of the cell cycle allowing live imaging. In collaboration with Prof. Miyawaki and Dr. Sakaue-Sawano I have developed polycistronic versions of these cell cycle probes allowing the generation of single Cre-inducible mouse strains. The first line developed (R26R-Fucci2a) is now available through the Riken BRC (RBRC06511) and EMMA (EM:08395) mouse repositories.
Current Teaching
Biol 124 – Hormones and Development
Biol 272 – Cell Biology Techniques (Module Organiser)
Biol 211 – Cell Biology
PhD Supervision Interests
I can offer PhD and MSc by research projects on either melanocytes and melanoma or cell/tissue biosensors. Please contact me for further details.
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01/01/2026 → 31/12/2026
Research
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01/08/2025 → 31/07/2026
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01/10/2024 → 30/09/2028
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01/10/2024 → 31/03/2028
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01/10/2024 → 30/09/2025
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01/09/2024 → 29/02/2028
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01/11/2021 → 31/10/2022
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01/10/2021 → 30/09/2023
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27/08/2021 → 26/08/2024
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01/10/2020 → 30/09/2024
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07/01/2020 → 06/07/2023
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01/10/2019 → 31/03/2020
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01/07/2019 → 30/09/2020
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01/08/2018 → 31/03/2020
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31/03/2018 → 30/11/2019
Research
School Engagement
Participation in conference -Mixed Audience
Hosting a Non-Academic Visitor
Business Engagement
Participation in workshop, seminar, course
Business Engagement
Business Engagement
Business Engagement
Types of Public engagement and outreach - Festival/Exhibition
Symposium
Symposium
Symposium
Oral presentation
Hosting an academic visitor
Participation in conference -Mixed Audience
Membership of committee
Types of Business and Community - Hosting of external, non-academic visitor
Types of External academic engagement - Hosting an academic visitor
Types of External academic engagement - Hosting an academic visitor
Types of Business and Community - Hosting of external, non-academic visitor
Types of External academic engagement - Hosting an academic visitor
Types of External academic engagement - Hosting an academic visitor
Types of Business and Community - Hosting of external, non-academic visitor
Types of Business and Community - Hosting of external, non-academic visitor
Types of Business and Community - Hosting of external, non-academic visitor
Types of Business and Community - Hosting of external, non-academic visitor
Types of Business and Community - Hosting of external, non-academic visitor
Types of Business and Community - Hosting of external, non-academic visitor
Business Engagement
Hosting a Non-Academic Visitor
Types of Business and Community - Hosting of external, non-academic visitor
Other
Prize (including medals and awards)
- Ageing and Neuroscience
- Cancer Biology and Genome Stability